Myeloma Chat & Online Support Group > WELCOME! > Myeloma Chat > Diagnosed with MGUS 10 months ago on (02/08)
Myeloma Chat & Online Support Group > WELCOME! > Myeloma Chat > Diagnosed with MGUS 10 months ago on (02/08) |
|
| Questions about this chat? Send a message to: Chat Moderator | ||
| Author | Post | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
SusieQ Member
|
My 42 year old husband was dx'd with MGUS earlier this yr. and has had lab tests repeated every 3 months since then. His free light chain levels: KAPPA - have ranged between 60-70 while his LAMBA free light chains have decreased from 11.3 to 3.19 increasing his kappa/lamba ratio to 3 times more than what it was initially from 6.29 to 20.50. He had a left hip bone marrow biopsy in February with a mild 8% plasmacytosis and small monoclonal paraprotein(1.15 gm/dl) of IgG kappa type. His beta- 2 microglobulin has varied from 2.20, 4.93*, 2.45, 2.21, to 2.56. My husband was told to return in 3 to 4 months for retesting. He has been told he just needs to wait and see what happens and/or to return sooner if he has any bone pain.He has had an MRI of his head and his low back for complaint of chronic pain in these areas. A routine physical and pain prompted the initial testing (SPE & IEP). Is there anyone who can elaborate on these results and what they mean exactly, and at what levels, if any, we should be worried about as his xrays have not showed any bone lesions. Any information is greatly appreciated. |
|||||||||
|
Chat Moderator Administrator 
|
Hi SusieQ, I spoke with Dr. Guido Tricot, the director of Huntsman Cancer Institute's Myeloma Program, about your posting and he says it is important for your husband to have either a PET/CT scan or MRI of his spine, pelvis, sternum, shoulders, and skull to see if there are myeloma lesions present. If there are, then this would indicate that your husband has progressed beyond MGUS and has myeloma that needs to be treated. There are no major increases in kappa free light chains, so it is possible that your husband is indeed stable and the MGUS has not progressed. Getting an MRI or PET/CT will be key in determining what is going on and getting you the answers you are seeking about his condition. All the best, HCI Myeloma Chat Moderator |
|||||||||